… HSP70 neuroprotection in brain injury (ischemic stroke and traumatic brain injury (TBI)), along
with pharmacological HSP70 … CHIP, an ubiquitin ligase, interacts with HSP70 by rounding …

… neuroprotective effects of HSP70 in stroke and brain trauma models. … brain undergoes a
stress response after cerebral ischemia (… CHIP is a ubiquitin ligase that interacts with HSP70 and …

… In cerebral ischemia in rats, neurons expressing Hsp70 have … latter with the participation of
the ubiquitin ligase CHIP, which … In this study, the Hsp70 level begins to increase shortly after …

… reflect the pathophysiological features in brain following IS. Therefore, more potent biomarkers
from … exosome secretion (eg, HSP70) improve ischemic tolerance by preconditioning …

… role of protein ISGylation after transient cerebral ischemia [7]. … gene expression and impaired
functional recovery after … ISGylation of ubiquitin E3 ligase CHIP (carboxyl terminus of Hsp70-…

… Western blot analysis of the expression of HRD1, HSP70 and ubiquitin in lysates of control
or … [61] and in cortical neurons following focal cerebral ischemia [62, 63]. In the models of …

… activity; (2) upregulation of gene expression that encode ER … and IRE1-UPR pathways after
cerebral ischemia, while ATF6 … which interacts with ubiquitinated proteins and selectively …

… cortical plasticity occurring after focal cerebral ischemia [14]. … against cerebral ischemic
insult through Hsp70-mediated … gene expression response and worsens functional outcome …

… ubiquitination levels of NLRP3. NSC-derived EVs inhibited the … processes through regulating
gene expression or protein … of EV-positive indicators CD9, TSG101, and HSP70, while …

… of maturation phenomena following brain ischemia. Despite … produced by HSP70 and studies
using HSP70 staining as a … , HSP70 forms a surface which packs misfolded ubiquitinated …